GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | C22orf32 | chr22:42475699-42480287:+ | -0.45 | -6.2 | 1.2E-9 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | HPS4 | chr22:26847447-26879820:- | -0.54 | -6.34 | 5.46E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | LOC284900 | chr22:28315364-28404267:+ | -0.42 | -6.27 | 8.2E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | POLDIP3 | chr22:42979728-43010962:- | -0.5 | -6.37 | 4.35E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | PPIL2 | chr22:22020273-22052201:+ | -0.5 | -5.91 | 6.68E-9 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | SAMM50 | chr22:44351261-44392411:+ | -0.52 | -6.55 | 1.54E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | SLC2A11 | chr22:24199059-24227723:+ | -0.62 | -6.32 | 6.15E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | TUBGCP6 | chr22:50656118-50683400:- | -0.39 | -5.98 | 4.32E-9 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | TXN2 | chr22:36863093-36877687:- | -0.48 | -6.5 | 2.05E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | UBE2L3 | chr22:21921957-21978323:+ | -0.49 | -6.15 | 1.68E-9 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | XRCC6 | chr22:42017295-42060052:+ | -0.52 | -6.41 | 3.4E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12157904 | 1 | rs12158264 | chr22:38001504 | ZMAT5 | chr22:30126946-30163000:- | -0.42 | -6.58 | 1.22E-10 | Response to anti-depressant treatment in major depressive disorder |
| THCA | trans | rs12209877 | 1 | rs12209877 | chr6:21027761 | CAMSAP1 | chr9:138700334-138799005:- | -0.2 | -6.04 | 3.02E-9 | Cognitive function |
| THCA | trans | rs1814175 | 1 | rs12293522 | chr11:49558425 | FOLH1B | chr11:89392465-89431885:+ | -0.35 | -6.23 | 1.01E-9 | Height |
| THCA | trans | rs1056667 | 1 | rs12526680 | chr6:26550954 | ZNF322B | chr9:99957633-99961910:- | 0.55 | 10.75 | 2.86E-24 | Educational attainment |